This song is actually very worshipful and if you read on the lifehouse official website Jason Wade the writer talks about how this is a form of crying out to God in desperate times... That in itself is nothing more than the purest of worship. In fact it reminds me very much of the woman who through herself at Jesus' feet and broke the jar of expensive perfume. It was a cry of commitment, desperation, and passion. That is what this song is about. Read the lyrics again and you'll see, Just 'cause it doesn't say Jesus on the box, doesn't mean it isn't Jesus in the box... There are many worship songs that don't say "Jesus" in it.
I have never done this song in Worship at church although I would much like to, however It's not really a song that falls under the CCLI liscence so there might be a bit of a legal issue with posting the words on a PowerPoint slide show, however I have performed the song at a Wedding, and it went fairly well.
Great song, and don't be mistaken on the writings of Lifehouse, despite what most people think their songs really arn't about girls.