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The key to great tone is really found in the kind of hand soap that you use.
For years I used a typical off-the-shelf bar-type soap and I had no idea that, even though I rinsed properly and thoroughly after every cleansing, there was still a soap scum residue on my hands and fingers.
This negatively affected my tone in ways that I just can't describe.
Then, on a whim, a few years ago I wandered into a Bath and Body Works store at a local mall and picked up some of their gentle foaming anti-bacterial hand cleansers.
The difference in my guitar's sound is so wickedly improved that I no longer feel the need to buy a new amp or pedals or even strings...EVER!
So, it's my belief that tone is in the soap.
Thank you and goodnight.